Publications by authors named "V Stoico"
Aims: We investigated quantitative expression, mutual aggregation and relation with hyperglycemia of insulin resistance (IR) and beta-cell dysfunction (BCD) in newly diagnosed type 2 diabetes.
Methods: We assessed IR with euglycemic hyperinsulinemic clamp and BCD with modelled glucose/C-peptide response to oral glucose in 729 mostly drug-naïve patients. We measured glycated hemoglobin, pre-prandial, post-prandial and meal-related excursion of blood glucose.
Background: Diabetic foot ulceration is a severe complication of diabetes characterized by chronic inflammation and impaired wound healing. This study aimed to evaluate the effect of a medical device gel based on adelmidrol + trans-traumatic acid in the healing process of diabetic foot ulcers.
Methods: Thirty-seven diabetic patients with foot ulcers of mild/moderate grade were treated with the gel daily for 4 weeks on the affected area.
Article Synopsis
- Nephropathy is a serious complication of type 2 diabetes (T2DM) linked to increased albuminuria and decreased glomerular filtration rate (GFR), with varying progression rates to severe kidney disease among patients.
- In a study of 410 newly diagnosed T2DM patients, researchers tracked changes in eGFR over an average of 12.4 years, finding that about 11.4% experienced rapid declines in eGFR.
- The study concluded that albuminuria is a strong predictor of rapid eGFR decline, which could help in identifying patients at risk and potentially slowing the progression of kidney damage.
Article Synopsis
- The study examined chronic complications in 806 newly diagnosed type 2 diabetes patients at the Verona Diabetes Clinic, focusing on both metabolic and clinical features.
- Comprehensive assessments were conducted to evaluate microvascular and macrovascular complications, including medical history, ECG, imaging tests, and insulin sensitivity analyses.
- Findings revealed that nearly 50% of patients had some form of complications, with key factors such as age, gender, and insulin resistance linked to these issues.
Honey dressing on a leg ulcer with tendon exposure in a patient with type 2 diabetes.
Endocrinol Diabetes Metab Case Rep
November 2018
Honey has been used as a wound dressing for hundreds of years by ancient civilizations, but only recently it has acquired scientific interest because of its relevant biological properties. In the last decade, indeed, several trials and observational studies have reported that, compared to conventional treatment (e.g.
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