Publications by authors named "V Stoeva"

Dental personnel are potentially exposed to pathogenic microorganisms, as well as to possible sources of infection. The same is true for dental students, for whom it is crucial to acquire knowledge on infection control and appropriate dental techniques during their training.

View Article and Find Full Text PDF
Article Synopsis
  • Capsicum peppers are economically significant due to their unique metabolites that impact both human health and plant interactions, but the genetic basis for these metabolites is not fully understood.
  • A genome-wide association study and a new mapping population were used to uncover over 1,000 metabolic quantitative trait loci (mQTL) for more than 250 metabolites, along with identifying 92 candidate genes linked to these traits.
  • The research specifically highlighted a gene cluster that contributes to the biosynthesis of capsianosides, providing insights into plant resistance and setting a foundation for future research on metabolite production in different species.
View Article and Find Full Text PDF

The aim of this study was to analyze the therapeutic results and survival of patients with myelofibrosis treated with ruxolitinib in comparison with a group on standard therapy. It is a cross-sectional, retrospective, non-interventional, real-life study that was performed between January 2000 and February 2023. Patients treated between 2000 and 2016, before the introduction of ruxolitinib, constituted the control group ( = 45), while those treated after May 2016, after ruxolitinib inclusion, constituted the active group ( = 66).

View Article and Find Full Text PDF

We aimed to explore symptom severity and adherence to therapy for patients with myelofibrosis treated with ruxolitinib in Bulgaria. It is a prospective, non-interventional study performed at the specialized hospital for active treatment of hematological diseases in Sofia during 2022-2023. Date of diagnosis, demographic characteristics, clinical indicators, ruxolitinib dose, and other data points were collected.

View Article and Find Full Text PDF

BACKGROUND Hemophagocytic lymphohistiocytosis (HLH) is a rare syndrome. It is a result of uncontrolled hyperactivation of the reticuloendothelial system with a release of a huge amount of proinflammatory cytokines in the bloodstream, causing a cytokine storm. It may be primary due to genetic defects and secondary, triggered by viruses, bacteria, parasites, lymphoproliferative, and autoimmune diseases.

View Article and Find Full Text PDF