Publications by authors named "V Souchard"
Article Synopsis
- Identifying key risk factors in childhood cancer survivors is crucial for improving treatment and follow-up care to reduce long-term mortality.
- A study of 7,670 childhood cancer survivors revealed that subsequent cancers, severe heart conditions, and radiotherapy significantly impact Life Years Lost.
- Radiotherapy was identified as a major cause of early death, highlighting the need for ongoing monitoring of patients who develop additional health issues post-treatment.
Purpose: Childhood cancer survivors, in particular those treated with radiation therapy, are at high risk of long-term iatrogenic events. The prediction of risk of such events is mainly based on the knowledge of the radiation dose received to healthy organs and tissues during treatment of childhood cancer diagnosed decades ago. We aimed to set up a standardized organ dose table to help former patients and clinicians in charge of long-term follow-up clinics.
View Article and Find Full Text PDFBackground: Optic pathway gliomas (OPGs) represent 5% of childhood brain tumors. Successive relapses lead to multiple treatments exposing to late complications.
Methods: We included patients treated at Gustave Roussy (GR) between January 1980 and December 2015 for OPG, before 18 years old and alive at 5 years from diagnosis.
Background: Childhood cancer survivors (CCS) are at an elevated risk of developing both a second malignant neoplasm (SMN) and cardiac disease.
Objectives: This study sought to assess the excess of occurrence of cardiac disease after a SMN among CCS.
Methods: Analyses included 7,670 CCS from the French Childhood Cancer Survivors Study cohort diagnosed between 1945 and 2000.
Article Synopsis
- A study examined how well long-term childhood cancer survivors at high risk for cardiomyopathy followed cardiac screening guidelines, involving nearly 1,000 patients.
- Only 32% of participants had an echocardiogram in the last five years, with lower adherence among males, older survivors, and those with specific cancer types like Neuroblastoma and CNS tumors.
- Attending long-term follow-up visits significantly increased the likelihood of completing echocardiograms, highlighting the need for better strategies to encourage more survivors to participate in recommended cardiac surveillance.