Estimating the impact of improved management of haemophilia a on clinical outcomes and healthcare utilisation and costs.

Objective: Haemophilia A (HA) is associated with high clinical and healthcare burden. We developed an Excel-based model comparing current practice to improved management in severe HA patients currently managed on demand (OD). Outcomes included short- and long-term bleed events.

Breakthrough Bleeding Episodes at Minimum and Improvement in Quality of Life in a Child with Severe Hemophilia A with Inhibitors Treated with Emicizumab: A Case Report from Chile.

BACKGROUND People with hemophilia A have shown osteomuscular complications that have a significant impact on their quality of life (QoL) and on health care costs. Patients with hemophilia A with inhibitors living in developing countries such as Chile face a high disease and treatment burden. Emicizumab, a humanized bispecific monoclonal antibody, is associated with improvements in QoL and reduction in the financial impact of the disease related to treatment.

Impact of Visual Biofeedback of Trunk Sway Smoothness on Motor Learning during Unipedal Stance.

The assessment of trunk sway smoothness using an accelerometer sensor embedded in a smartphone could be a biomarker for tracking motor learning. This study aimed to determine the reliability of trunk sway smoothness and the effect of visual biofeedback of sway smoothness on motor learning in healthy people during unipedal stance training using an iPhone 5 measurement system. In the first experiment, trunk sway smoothness in the reliability group ( = 11) was assessed on two days, separated by one week.

Knee haemophilic arthropathy care in Chile: Midterm outcomes and complications after total knee arthroplasty.

Introduction: Total knee arthroplasty (TKA) can improve knee function in the general population, but challenges arise for TKA use in haemophilic patients (HPs).

Aim: This study aimed to evaluate the midterm clinical experience of a single medical centre in TKA in HPs.

Methods: We performed a case series of consecutive TKAs from 2007 to 2013 in HPs.

Effects of performing dual tasks on postural sway and postural control complexity in people with haemophilic arthropathy.

Introduction: People with haemophilic arthropathy (PWHA) have impairments in postural control. However, little is known about the effects of demanding conditions, including the unipedal stance and dual tasks, on postural control in PWHA.

Aim: Determine the effects of performing dual tasks while in the one-leg stance on postural sway and postural control complexity in PWHA vs.