Combining physostigmine with meperidine for sedation and analgesia during colonoscopy.

Background And Study Aim: Opiate or benzodiazepine drugs are often used during colonoscopy, but they are associated with respiratory depression and prolonged recovery. Physostigmine, a tertiary anticholinesterase agent, is known to enhance analgesia and to reverse the central nervous system depressant effects of these drugs. This study compared the effect of giving meperidine alone with the effect of giving meperidine in combination with physostigmine in patients who were undergoing complete colonoscopy.

Comparison of the Flexiblade levering laryngoscope with the English Macintosh laryngoscope in patients with a poor laryngoscopic view.

The effectiveness of two laryngoscopes, the English Macintosh and the Flexiblade (a levering laryngoscope), were compared in a clinical setting. An investigation was carried out in 100 patients admitted for surgery under general anaesthesia, to compare intubation with the Flexiblade or the Macintosh laryngoscope. The patients had two anatomical characteristics that may predict difficult intubation - Mallampati score II and III, and a thyromental distance View Article and Find Full Text PDF

Design evaluation of commonly used rigid and levering laryngoscope blades.

Background: The shape of a laryngoscope blade affects the exposition of the larynx. This study evaluates and compares some rigid and levering blade designs based on previous investigative X-ray laryngoscopic studies.

Methods: Five rigid laryngoscope blades (Miller #3, Standard Macintosh #3, Classical Macintosh #4 and English-Macintosh #3 and #4) and two levering laryngoscope blades (McCoy in neutral and maximally elevated positions and Flexiblade in three basic positions: straight, neutral, and maximally curved) were evaluated.