Publications by authors named "V Singam"

Article Synopsis
  • Lipofibromatosis-like neural tumors (LPF-NTs) are a new type of spindle cell tumors, characterized by a unique pattern and specific markers like CD34 and S100, as well as genetic changes involving the NTRK1 gene.
  • A case study is presented involving an 11-year-old patient with LPF-NT showing a distinct honeycomb pattern similar to dermatofibrosarcoma protuberans, along with specific co-expressions and gene rearrangements.
  • The paper also reviews 73 previously documented cases of LPF-NT to highlight the evolving understanding of this tumor type.
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Background: Patient-Reported Outcomes Measurement Information System Global Health (PGH) was validated to assess health-related quality of life in several diseases. Little is known about its measurement properties in adult atopic dermatitis.

Objective: Examine the measurement properties of PGH in adult atopic dermatitis.

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Background: Few outcome measures were validated for assessing depressive symptoms in AD. Patient Health Questionnaire-9 (PHQ9) and the abridged PHQ2 are established patient-reported outcome measures of depressive symptoms.

Objective: We sought to examine the measurement properties of PHQ9 and PHQ2 in adult AD.

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Background: Multiple strategies have been used to evaluate the minimal important change (MIC) of the Eczema Area and Severity Index (EASI) and Scoring Atopic Dermatitis (SCORAD). The meaningfulness of these MICs is not well established across all severities of atopic dermatitis (AD).

Objectives: To determine the MIC of percentage and absolute improvement of EASI and SCORAD scores in adults and children with AD.

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