Disorders of the Biochemical Composition of the Periodontium in Rats with Periodontitis and Chronic Pain Syndrome.

We analyzed the composition of the periodontal tissue in rats with experimental periodontitis and chronic pain syndrome. Chronic pain syndrome was induced by bilateral ligation of the sciatic nerve; experimental periodontitis was modeled by application of eight-shaped silk thread ligature to lower jaw incisors followed by its immersion into the periodontal groove and fixation with additional knots. A decrease in the concentration of oxyproline, glycosaminoglycans, and catalase activity and an increase in the content of malondialdehyde and acylhydroperoxides in the periodontal tissue were found in animals with experimental periodontitis throughout the experiment (7-21 days).

Correction of Acute Parodontitis with Indolicidin Analogues.

We studied the influence of synthetic indolicidin analogues on the development of acute periodontitis. The corrective effect was found in indolicidin analogues Nos. 7 and 8; it manifested in a decrease in the edema of gingival epithelium and lamina propria, a decrease in the relative area of inflammatory infiltrates, and a significant increase in the relative area of normal connective tissue.

[Mild cognitive disorders in railway locomotive crew workers (review of literature)].

Functional reliability of engine operator and engine operator's assistant is one of the most important factors in railway safety. Ability to railway locomotive operation is determined via suitability criteria of occupationally important qualities of operator and operator's assistant, and of nervous system functional state. Lower reliability manifested in worse functional state of engine operator or in lost occupationally important qualities can be connected with various diseases of which most prevalent are cardiovascular disorders.

[Evaluating influence of Captopril therapy on occupational activity of engine operators with hypertension].

The article covers results of study concerning influence of Captopril (25 mg) therapy on occupational activity of locomotive crew workers in real night travels model on training complex "EP1M locomotive operator cabin". Findings are that single use of Captopril (25 mg) in modelled railway activity enabled to increase reliability of occupational activity, that manifested in lower number of errors in locomotive operators' actions at night, and in psychophysiologic regulation of various psychic acts.

[Possible psychoemotional correction of psychophysical state in railway locomotive crew workers].

The article presents results of study concerning influence of relaxation sessions on emotional and psychophysical state of locomotive crew workers in special cabin for psychoemotional relief "Vivid silence" simulating rest in nature. Relaxation sessions appeared to cause better mood, lower blood pressure, increased reactions speed, reduced number of errors. Purposeful training of the specialists in self-regulation is extremely important for preparation to work activity and for prophylactic and social measures aimed to preserve and improve health in locomotive crew workers.