Publications by authors named "V Seija"
Article Synopsis
- The study examines the presence of antimicrobial resistance in Uruguay, specifically focusing on 16S ribosomal RNA methylases that confer significant resistance to aminoglycosides.
- Five bacterial isolates from patients across three hospitals were analyzed using advanced genomic techniques to identify antibiotic susceptibility and resistance mechanisms.
- The findings reveal the first detection of specific plasmids containing resistance genes in Uruguay, highlighting the serious health risks posed by multidrug-resistant organisms due to limited effective treatment options.
is a leading cause of hospital-acquired infections worldwide. Biofilm production, antibiotic resistance, and a wide range of virulence factors contribute to their persistence in nosocomial environments. We describe an outbreak caused by a multidrug-resistant strain in an ICU.
View Article and Find Full Text PDFAntibiotic resistance is an alarming problem throughout the world and carbapenem-resistant has been cataloged as critical in the World Health Organization list of microorganisms in urgent need for the development of new antimicrobials. In this work, we describe two novel resistance regions responsible for conferring a multidrug resistance phenotype to two clinical isolates of (Pa873 and Pa6415) obtained from patients hospitalized in the ICU of University Hospital of Uruguay. Bacterial identification and antibiotic susceptibility tests were performed using MALDI-TOF and the Vitek 2 system, respectively.
View Article and Find Full Text PDFArticle Synopsis
- - The study analyzed 27 mecA positive Staphylococcus aureus strains from various regions in Uruguay, focusing on their phenotypic and genotypic characteristics, particularly regarding oxacillin resistance.
- - Most strains were found to be susceptible to oxacillin; however, 25 strains showed resistance to methicillin through different testing methods, with PBP2a detection confirming MRSA status in most cases.
- - Genetic analysis revealed that 26 strains carried SCCmec type V, indicating a widespread cluster of MRSA, and one strain exhibited a different SCCmec type IV.