Publications by authors named "V Savica"

In ancient times, religious traditions considered urine a useful distilled product from the body. It has been used as a form of medicinal therapy for many years and is still used by millions of people worldwide who drink their urine for therapeutic purposes. The positive effects of urine on health were reported since the Renaissance for its bactericidal effects on wounds, healing effects on gastric ulcers, improved protein synthesis, regression of liver tumors, and ability to block the growth of tuberculosis mycobacteria.

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Horseshoe kidney or ren arcuatus is the most common renal fusion anomaly, with an incidence of 1:500 in the normal population and a male predominance of 2:1. In >90% of cases, the fusion occurs along the inferior pole. It may vary in location, orientation, and arterial and venous anatomy.

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Jeronimo Ruscelli was a mysterious humanist of great fame. He was born in Viterbo between 1504 and 1518 and died in Venice in 1566. Very little is known about Ruscelli's life, but based on his extensive literary output we can assume that he was endowed with remarkable intellectual abilities and a propensity for varied interests.

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Franz Volhard (May 2, 1872, to May 24, 1950) was a German clinician and researcher who made outstanding contributions to the field of nephrology and hyper-tension. His studies led to important developments in knowledge about the pathophysiology of the kidney and its relationship to cardiovascular disease. He contributed to a better understanding of the mechanisms underlying renovascular hypertension by explaining the crucial relationship between the decrease in renal blood flow and the increase in blood pressure.

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Article Synopsis
  • The progression of autosomal-dominant polycystic kidney disease (ADPKD) varies within families, hinting that environmental factors could influence disease development.
  • Investigating the effects of calcium oxalate (CaOx) crystal deposition, researchers found that it accelerated disease symptoms by causing tubule dilation and activating certain signaling pathways in the kidneys.
  • In both rat models and human patients, lower urinary excretion of citrate, which helps prevent crystal formation, was linked to faster disease progression, indicating that managing crystal deposits could potentially slow down PKD progression.
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