Publications by authors named "V Savelli"
Article Synopsis
- Immune-checkpoint inhibitors (ICIs) can cause immune-related adverse events (irAEs), with immune-mediated pneumonitis (im-PN) being a rare but serious complication that requires prompt diagnosis and management to prevent severe outcomes and allow for continued cancer treatment.
- A study collected data from 1004 cancer patients treated with ICIs, finding that 24 (2%) developed im-PN, with varying degrees of severity; most patients responded well to steroid treatment, leading to recovery in 21 individuals within an average of 14 weeks.
- Three main radiologic patterns of im-PN were identified (organizational pneumonia-like, pulmonary eosinophilia, and hypersensitivity pneumonitis), and bronchoalve
Background And Objectives: Only recently the percentage of signet ring cells (SRCs) in gastric cancer (GC) has been proposed as an independent predictor of survival. High amounts of SRCs have been related to lower recurrence and mortality rates, better prognosis, and favorable clinicopathological features in a poorly cohesive histotype. It is not known what the effect of SRC percentage in mixed-type GC is.
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- This study examines how frailty, rather than just age, affects surgical outcomes in patients undergoing elective abdominal surgery, emphasizing handgrip strength (HGS) as a useful indicator of frailty.
- Researchers found that out of 108 patients, a significant portion were categorized as pre-frail or frail, with lower HGS values linked to these groups compared to fit individuals.
- The results indicate that HGS is a reliable predictor of hospital length of stay (LOS), highlighting its potential role in enhancing surgical decision-making and patient care.
Surgical site infection occurs with high frequency in gastrointestinal surgery, contributing to the high incidence of morbidity and mortality. The accepted practice worldwide for the prevention of surgical site infection is providing single- or multiple-dose antimicrobial prophylaxis. However, most suitable antibiotic and optimal duration of prophylaxis are still debated.
View Article and Find Full Text PDFPurpose: Non-occlusive mesenteric ischemia (NOMI) is a misdiagnosed and dangerous condition. To our knowledge, a comprehensive evaluation of CT parameters that can predict the outcome of patients suffering from NOMI is still missing.
Materials And Methods: Contrast-enhanced CT examination of 84 patients with a confirmed diagnosis of NOMI (37 with clinical and laboratory confirmation and 47 biopsy or surgery proven) was retrospectively reviewed by assessing vessels, mesentery, bowel, and peritoneal cavity CT quantitative and dichotomous parameters, and data were analyzed with Fisher's test.