Publications by authors named "V Sambri"
Article Synopsis
- Novel antimicrobial drugs, like cefiderocol, have been developed to tackle the rise of antimicrobial resistance, specifically against multidrug-resistant (MDR) Gram-negative bacilli (GNB).
- Cefiderocol, a unique siderophore cephalosporin, efficiently penetrates bacterial outer membranes, making it effective against various resistance strategies and offering a broad spectrum of action.
- Despite its effectiveness, recently identified cefiderocol-resistant strains highlight the need for new strategies in clinical practice to maintain its antibacterial efficacy.
In the last 6 years, Italy accounted for 36 % of the total autochthonous European West Nile virus (WNV) cases reported to ECDC. Since 2001, the country put in place a multi-species national surveillance plan. The plan was enhanced in 2020 by adopting a fully integrated "One Health" approach, including human, wild bird, equine, and mosquito surveillance for the early detection of WNV.
View Article and Find Full Text PDFThe freshwater environment is suitable for nontuberculous mycobacteria (NTMs) growth. Their high adaptability represents a considerable risk for sanitary water systems, which are a potential vector for NTMs transmission. This study investigated the occurrence of NTMs, such as , in hospital water systems to support the surveillance and control of potentially pathogenic NTMs.
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- * A 42-year-old male patient presented with various symptoms such as vomiting and abdominal pain, and initial diagnoses included pancreatitis, later revealing lung issues through CT scans and blood cultures.
- * This case marked the first documented human infection by this particular bacterium in Italy; the identification was challenging due to the rarity of cases and nonspecific symptoms, but was successfully achieved through advanced genetic testing methods.
, identified in 2006, represents a challenging case of bacterial taxonomic identification because of its high similarity to . In this context, neither mass spectrometry (MS) nor 16S gene analysis cannot precisely reveal the difference between the two species. In our study, the sensitivity to antibiotics of isolated from blood culture was tested, and the investigation of the bacterial genome was performed by Multi-Locus Sequence Typing (MLST) and Whole-Genome Next-Generation Sequencing (WG-NGS).
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