Innovative bioinks for 3D bioprinting: Exploring technological potential and regulatory challenges.

The field of three dimensional (3D) bioprinting has witnessed significant advancements, with bioinks playing a crucial role in enabling the fabrication of complex tissue constructs. This review explores the innovative bioinks that are currently shaping the future of 3D bioprinting, focusing on their composition, functionality, and potential for tissue engineering, drug delivery, and regenerative medicine. The development of bioinks, incorporating natural and synthetic materials, offers unprecedented opportunities for personalized medicine.

Imaging melanin-associated organelles in the retinal pigment epithelium via visible light OCT redshift.

The retinal pigment epithelium (RPE) performs a number of functions essential for retinal health. RPE dysregulation and degeneration can occur in diseases. Methods to image the human RPE directly are limited, as it is only about 10 µm thick and situated between the photoreceptor outer segments and Bruch's membrane (BM).

Unveiling the Role Reversal of Guest and Host in OverTolerant Hybrid Perovskites.

The structural and electronic changes are investigated in a 3D hybrid perovskite, methylhydrazinium lead chloride (MHyPbCl) from a host/guest perspective as it transitions from a highly polar to less polar phase upon cooling, using first-principles calculations. The two phases vary structurally in the guest (MHy) orientation and the two differently distorted host (lead halide) layers. These findings highlight the critical role of guest reorientation in reducing host distortion at high temperatures, making the former the primary order parameter for the transition, a notable contrast to the case of other hybrid perovskites.

Multicenter analysis of the incidence of in-stent stenosis following the deployment of flow-redirection endoluminal device in the treatment of intracranial aneurysms.

Introduction: The Flow Re-direction Endoluminal Device (FRED) is a novel flow diverter with a unique double stent design, with an inner stent composed of 48 nitinol wires, and an outer stent with 16 nitinol wires. It is designed for endovascular cerebral aneurysm treatment, although, limited data exist regarding in-stent stenosis (ISS) rates associated with FRED devices.

Methods: A registry encompassing two North American comprehensive stroke centers was the base of this study.