The narrow escape problem of a chiral active particle (CAP): an optimal scheme.

We report a simulation study on the narrow escape kinetics of a chiral active particle (CAP) confined to a circular domain with a narrow escape opening. The study's main objective is to optimize the CAP's escape chances as a function of the relevant parameters, such as translational and rotational speeds of the CAP, domain size, We identified three regimes in the escape kinetics, namely the noise-dominated regime, the optimal regime, and the chiral activity-dominated regime. In particular, the optimal regime is characterized by an escape scheme that involves a direct passage to the domain boundary at first and then a unidirectional drift along the boundary towards the exit.

Revealing the deterministic components in active avalanche-like dynamics.

Avalanche dynamics in an ensemble of self-propelled camphor boats are studied. The self-propelled agents are camphor infused circular paper disks moving on the surface of water. The ensemble exhibits bursts of activity in the autonomous state triggered by stochastic fluctuations.

A DNAzyme based knockdown model for Fragile-X syndrome in zebrafish reveals a critical window for therapeutic intervention.

Introduction: FXS is the leading cause of intellectual disabilities in males and a major monogenic cause of ASD (Autism spectrum disorders). It occurs due to the loss of FMRP, whose role in early development is not well understood. In this study, we have used a novel DNAzyme based approach to create a larval model of FXS in zebrafish with specific focus on the early developmental window.

Phase separation in binary fluid mixtures with symmetric and asymmetric Schmidt numbers: A DPD study.

We investigate the effect of the Schmidt number (Sc) on phase separation dynamics of two immiscible fluids in a two-dimensional periodic box using dissipative particle dynamics. The range of Sc investigated spans liquid-liquid separation processes. Phase separation is characterized by a domain size r(t), which typically follows a power law t in time t, where β is a characteristic exponent corresponding to the coarsening mechanism at play.