Publications by authors named "V S Pal"

Introduction: Delirium is a common and serious neuropsychiatric syndrome characterized by acute, fluctuating alterations in consciousness, cognition, and perception. It is associated with increased morbidity, mortality, length of hospital stays, and healthcare costs.

Aim:  The aim of this study was to assess the prevalence and clinical profile of psychiatric referrals of delirium in a tertiary-care hospital.

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Background The presence of psychiatric symptoms in pregnancy is a common occurrence that requires swift and effective management to avoid harm to self, caregivers, staff, and, above all, the reliant fetus. However, there is a dearth of knowledge, practical guidelines, and research in the context of managing agitated states of antenatal patients. To bridge this critical knowledge gap, this research endeavors to illuminate the practices surrounding the management of agitated pregnant women with respect to psychiatric emergencies in a tertiary care hospital.

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Background: Obsessive-compulsive disorder (OCD) is a significant mental condition characterized by the presence of obsessions and compulsions. Mental compulsions are defined as compulsions with no overt behavioral or motoric symptoms, such as repeating certain words or phrases in the mind. The exact prevalence of mental compulsions could be underestimated due to measurement issues using the Y-BOCS (Yale-Brown Obsessive Compulsive Scale) and its clinical characteristics.

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Article Synopsis
  • - Millions suffer from dry eye disease, a condition that worsens with age, characterized by an imbalance in tear film and classified into aqueous-deficit and evaporative types.
  • - The study emphasizes the challenges in drug delivery due to the eye's natural defenses, which limit the bioavailability of topical treatments, while also highlighting recent advancements in formulations for dry eye treatment.
  • - The review aims to provide a comprehensive overview of dry eye disease, including its causes, recent research findings, clinical data, and patents related to new treatment formulations.
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Importance: The role of olanzapine has not been adequately evaluated in moderately emetogenic chemotherapy (MEC) regimens with or without neurokinin-1 receptor antagonists.

Objective: To evaluate whether addition of olanzapine to an MEC regimen reduces nausea, vomiting, and use of nausea rescue medications among patients with solid malignant tumors.

Design, Setting, And Participants: This multicenter, open-label phase 3 randomized clinical trial included patients aged 18 years or older with solid malignant tumors who were receiving oxaliplatin-, carboplatin-, or irinotecan-based chemotherapy.

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