Publications by authors named "V S Nefedov"

The reproducibility of determining gases and acid-base balance (ABB) in the arterialized capillary blood taken by 1 and 2 earlap punctures at an 3-15-min interval for up to 7-28 days was studied in 171 subjects (16 healthy individuals and 155 patients with tuberculosis and other diseases of the lung. No relationship was found between the reproducibility of paO2, PaCO2, and SO2, the duration test intervals and that for BE, SB, and pH. The opinion as to the time course of changes in arterialized capillary blood gases and ABB may be regarded as justified only with the changes in paO2 > 4 mm Hg, paCO2 > 2 mm Hg, SO2 > 1%, BE > 0.

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Intraoperative (n = 290) and autoptic (n = 246) materials obtained from tuberculosis hospitals in 2005-2007 were examined to study the pathomorphism of pulmonary tuberculosis. The study revealed an increase in the number of patients with acute pulmonary tuberculosis. Fibrocavernous tuberculosis halved as compared to the 1980s.

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Vital capacity (VC), forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), FEV1/VC%, PEF, MEF25, MEF50, MEF75, TLC, TGV, residual volume (RV), R(aw), R(in), R(ex), DLCO-SB, DLCO-SS, PaO2, and PaCO2 were determined in 62 patients with chronic fibrocavernous tuberculosis. Lung dysfunctions were detected in 96.8% of the patients.

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Vital capacity (VC), forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), FEV1/VC%, PEF, MEF25, MEF50, MEF75, TLC, TGV, pulmonary residual volume (PRV), Raw, Rin, Rcx, DLCO-SB, DLCO-SS/VA, PaO2, and PaCO2 were determined in 40 patients with focal pulmonary tuberculosis. Changes were found in lung volumes and capacities in 75%, impaired bronchial patency and pulmonary gas exchange dysfunction were in 57.5 and 25%, respectively.

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