[Change in blood viscosity and hematocrit during cooling of an animal].

When studying temperature dependencies of rat's blood viscosity, cooled in vivo and in vitro, we have identified the differences in their nature. An attempt is made to evaluate contribution of hematocrit into a rise in the viscosity of rats being cooled.

[Properties of the adenylate cyclase system of isolated hepatocytes following freezing-thawing].

The effect of various regimen of freezing and thawing on the functional state of one of the most important receptor-regulatory cell systems, i. e. adenylate cyclase complex (ATP-pyrophosphate lyase cyclating E C 4.

[Effect of freezing-thawing on the adenylate cyclase activity of the rat liver].

Various regimes of freezing and thawing as well as adrenaline and fluoride ions are studied for their effect on the adenylate cyclase activity in liver tissue preparations. The reduction of basal and fluoride-stimulating adenylate cyclase activity and a decrease in the adrenaline-stimulating activity of the enzyme after freezing and thawing are shown. Freezing and thawing are studied for molecular mechanisms of their damaging effect on adenylate cyclase.

[Effect of the permeability of lysosomal and mitochondrial membranes on the ability of their cryoextracts to inhibit the protein-synthesizing activity of cell-free systems].

Changes in permeability of lysosomal and mitochondrial membranes were studied under different temperatures at which cryoextracts from organelles inhibit most distinctly the protein synthesizing activity of the cell-free system from the rat liver. It is found that mitochondria are more sensitive to the effect of low temperature effect than lysosomes. Overcooling of the mitochondria suspension to the temperature of the free water crystallization is shown to cause no release of the protein synthesis inhibitor.