[Quality of life in patients after operative treatment of infected pancreonecrosis].

The quality of life was studied up, using MOS SF-36 questionnaire in 47 patients, operated on for infected pancreonecrosis and its complications. Trustworthy lowering of quality of life was revealed in some indices of its physical component only, which were reduced, comparing with such in the patients of a control group.

[Boceprevir: new possibilities for antiviral treatment of chronic hepatitis C].

The given clinical review covers current antiviral therapy for chronic hepatitis C. Traditional antiviral therapy with pegylated interferon-alpha and ribavirin in patients with chronic hepatitis C virus genotype 1 allows a sustained virological response (SVR) to be achieved in no more than 40% of the treated patients. The practical introduction of the third component of the therapy as direct-acting antiviral agents makes it possible to substantially increase SVR, on the one hand, and to reduce treatment time, on the other hand.

[Clinical efficiency of high-dose interferon therapy in patients with chronic NCV hepatitis].

11 patients with confirmed chronic HCV-hepatitis were treated with high-dose interferon. 12 matched controls were treated conventionally. Higher response was registered in patients on the interferon treatment.

[Therapeutic response to alpha-interferon in chronic alcoholics with viral hepatitis C].

Hepatitis C was treated with interferon alpha in chronic alcoholics and control subjects without alcoholism. The results show that ethanol is an independent risk factor in natural progression of chronic hepatitis C. Moreover, it dose-dependently reduces probability of getting a reliable response to interferon therapy.

[Chronic viral infection in patients with alcoholic liver involvement].

Aim: Detection of viral hepatitides markers in patients with alcoholic damage to the liver.

Materials And Methods: Virological, immunological and histochemical tests were performed in 36 chronic alcoholics who had enlarged liver and/or abnormal hepatic characteristics.

Results: 60% of the examinees carried chronic HBV, HCV, HDV infection.