Publications by authors named "V S Kharasch"

The diaphragm is the major muscle of inspiration accounting for approximately 70% of the inspired tidal volume. Point-of-care diaphragmatic ultrasound offers the ability to quantitatively assess diaphragmatic function, perform serial evaluations over time, and visualize structures above and below the diaphragm. Although interest in point-of-care ultrasound (POCUS) of the diaphragm is developing in the emergency medicine, assessment of the diaphragm and its function is not recognized as a core application by national organizations or expert guidelines.

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Objective: This study aimed to describe daytime and nighttime use and outcome of non-invasive respiratory intervention (NIRI) for infants born prematurely and for children with medical complexity (CMC) during a post-acute care hospital (PACH) admission.

Methods: Thirty-eight initial PACH admissions (October 2018 through September 2020) for premature infants (< 1 year; n = 19) and CMC (> 1 year; n = 19) requiring NIRI during the day and/or at night were retrospectively examined. Measures included: 1) daytime and nighttime NIRI use by type (supplemental oxygen therapy via low-flow nasal cannula or positive airway pressure [PAP] via high-flow nasal cannula, continuous positive airway pressure, or biphasic positive airway pressure at admission and discharge) and 2) daytime and nighttime NIRI outcome-reduction, increase, or no change from admission to discharge.

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Article Synopsis
  • Children with medical complexity (CMC) are characterized by chronic health issues and a reliance on technology, leading to high healthcare use; this study explores the role of point-of-care ultrasound (POCUS) in diagnosing and managing these patients.
  • A total of 104 POCUS scans were carried out on 33 CMC patients, with the majority of cases related to congenital anomalies and neurologic conditions; lung and diaphragmatic evaluations made up the bulk of requests.
  • The results showed high abnormality rates in diaphragmatic (82%) and lung (73%) scans, indicating that POCUS is valuable for clinical assessments, follow-ups, and establishing baselines in postacute care settings.
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