Plasmonic random laser enabled artefact-free wide-field fluorescence bioimaging: uncovering finer cellular features.

Narrow bandwidth, high brightness, and spectral tunability are the unique properties of lasers that make them extremely desirable for fluorescence imaging applications. However, due to the high spatial coherence, conventional lasers are often incompatible for wide-field fluorescence imaging. The presence of parasitic artefacts under coherent illumination causes uneven excitation of fluorophores, which has a critical impact on the reliability, resolution, and efficiency of fluorescence imaging.

Bio-inspired wrinkle microstructures for random lasing governed by surface roughness.

A method for fabricating bio-inspired scattering substrates based on polydimethylsiloxane (PDMS) for spatially incoherent random lasing is presented. The leaves of monstera and piper sarmentosum plants are used to mold PDMS polymer to form wrinkle-like scattering substrates, which are then used with a liquid gain medium for random lasing. Scattering is attributed to the surface roughness () of the samples.

Stokes mode Raman random lasing in a fully biocompatible medium.

We demonstrate for the first time, to the best of our knowledge, Raman random lasing in a continuous-wave (CW) excited, completely biocompatible and biodegradable carrot medium naturally composed of fibrous cellulose scattering medium and rich carotene Raman gain medium. The CW-laser-induced photoluminescence threshold and linewidth analysis at the Stokes modes of carotene show a characteristic lasing action with a threshold of 130  W/cm and linewidth narrowing with mode Q factor up to 1300. Polarization study of output modes reveals that lasing mode mostly retains the source polarization state.

Femtosecond laser-pumped plasmonically enhanced near-infrared random laser based on engineered scatterers.

In this Letter, we report on the design, fabrication, and implementation of a novel plasmon-mode-driven low-threshold near-infrared (NIR) random laser (RL) in the 850-900 nm range based on plasmonic ZnS@Au core-shell scatterers. Plasmon modes in the NIR region are used for nanoscale scatterer engineering of ZnS@Au core-shell particles to enhance scattering, as against pristine ZnS. This plasmonic scattering enhancement coupled with femtosecond (fs) laser pumping is shown to cause a three-fold lasing threshold reduction from 325  μJ/cm to 100  μJ/cm and a mode Q-factor enhancement from 200 to 540 for ZnS@Au-based RL, as compared to pristine ZnS-based RL.