Personalized Assistance for Patients with Chronic Diseases Through Multi-Level Distributed Healthcare Process Assessment.

The study is aimed towards the assessment and improvement of complex informational, healthcare, and medical processes existing in the distributed environment during monitoring and providing healthcare services to patients with chronic diseases. The study is performed within a framework of a project for development a complex unified medical information system capable to work on large scale (on population-level). The presented experimental studies show that predictive modelling enables unified detection of remote patients' state using self-measuring and distributed electronic health records.

[Preparation of biologically transformed raw material from woolly foxglove Digitalis lanata Ehrh and isolation of digoxin from it].

A biotechnological approach is proposed for conservation of a terraneous part of woolly foxglove under anaerobic conditions with a subsequent air-sun drying of the biologically transformed raw material. During the conservation primary foxglove glycosides completely convert to secondary ones which do not transform further. A simple method is described for preparation from the transformed raw material of an enriched glycoside fraction with the yield of 3.

[The evolution of a contusion focus after the microsurgical autotransplantation of the omentum (an experimental study)].

The purpose of treatment of head trauma cannot be limited by simple life saving, it also should be targeted at the improvement of the quality of life. Twenty dogs with graded local head trauma underwent microsurgical revascularization of the area adjacent to the contused brain with an autologous omental graft to provide functional improvement. The effectiveness of surgery was demonstrated in series of 5 experiments when the operation was performed on posttraumatic days 7-14, with the follow-up of as long as 180 days.

[Cell cultured of Macleaya cordata--a producer of antimicrobial benzo[c]phenanthridine alkaloids].

It was shown that a suspension culture of Macleaya cordata accumulated benzo(c)phenanthridine alkaloids in the cell biomass. By the composition of the alkaloids and their content the cell culture markedly differed from the intact plant and callus tissue. The benzo(c)phenanthridine compounds in the cell culture were mainly represented by the reduced forms: dihydrosanquinarin and dihydrochelirubin.