[Neuroprotective effect of cerebrocurin in a model of acute cerebral stroke].

Chronic administration of cerebrocurin and cerebrolysin to Mongolian jirds with acute cerebral stroke model led to a decrease in the mitochondrial dysfunction on the 4th day, which was manifested by their ability to inhibit the mitochondrial permeability transition pore opening, normalize the energy metabolism, and enhance c-fos gene expression. In addition, cerebrocurin restored the morphofunctional state of neurons and favored the cell loss mechanism switching from necrosis to apoptosis. With respect to all characteristics under consideration, the effect of cerebrocurin exceeded with statistical confidence that of cerebrolysin.

[The structure of an aerogenic load and risk to human health in an industrial town's residential area].

Chemical air pollution of the residential and industrial areas of a town was evaluated. There was a significant relationship of the average daily actuating concentrations of priority substances to the air pollution of the study areas, the average annual concentrations of ambient air pollutants to their seasonal values. The structure of the risk to community health and the contribution of the industrial environment to the formation of a health risk were ascertained.

[Human health risk upon air exposure to chemicals in enclosed spaces and residential areas of an industrial town].

The study determined priority chemicals in the ambient air and air of enclosed spaces of the town's administrative districts, by taking into account the formation of a community health risk. The industrial town's areas were ranked by the hazard of carcinogenic and non-carcinogenic effects caused by the varying intraenvironmental distribution of substances. The distribution of pollutants in the study areas with varying anthropogenic exposures allows one to consider suspended matter, cadmium, nickel, and formaldehyde in the air of residential areas and formaldehyde, phenol, and suspended matter in the air of enclosed spaces as universal markers of exposure for dwelling environmental factors in the identification of toxicants and in the assessment of community health risk within the framework of sociohygienic monitoring and as indicators for the assessment of the immediate and final results of purpose-oriented departmental programs.

[The first break-through of the genotype 2.3.2 of high-virulence influenza A virus A/HSN1, which is new for Russia, in the Far East].

The epizootic etiologically associated with highly pathogenic avian influenza H5N1 genotype 2.3.2 that is new for Russia among wild and domestic birds in the south of the Primorye Territory during spring migration in April 2008 has been decoded.