Modifiable risk factors, oxidative stress markers, and SOD2 rs4880 SNP in coronary artery disease: an association study.

Background: Coronary artery disease (CAD) has been linked to single nucleotide polymorphism (SNP) in superoxide dismutase 2 (SOD 2) gene. Additionally, several modifiable risk factors are also known to influence the CAD risk.

Aim: To investigate the association between selected modifiable risk factors and oxidative stress markers with the SOD2 rs4880 SNP in CAD patients.

The relationship of lipid peroxidation and antioxidant status to selected modifiable risk factors in coronary artery disease patients.

Background: Coronary artery disease (CAD) is found to be associated with a wide range of modifiable and non-modifiable risk factors.

Aim Of The Study: To evaluate the relationship of lipid peroxidation and antioxidant status to selected modifiable risk factors in angiographically proven CAD patients.

Methods: 150 angiographically proven CAD patients were categorized into three, based on selected risk factors.

Effect of dual stimuli responsive dextran/nanocellulose polyelectrolyte complexes for chemophotothermal synergistic cancer therapy.

Dual stimuli responsive polyelectrolyte nanoparticles have been developed for chemo-photothermal synergistic therapy of colon cancer cells. This novel system is formed by layer by layer (LbL) assembly, which is composed of aminated nanodextran (AND) and carboxylated nanocellulose (CNC) deposited on the surface of chemically modified graphene oxide (MGO). The alternate layers of cationic AND and anionic CNC interact with MGO through electrostatic interaction and forms MGO-AND/CNC nanocomposite.

Characterizing and predicting coarse and fine particulates in classrooms located close to an urban roadway.

The PM10, PM2.5, and PM1 (particulate matter with aerodynamic diameters < 10, < 2.5, and < 1 microm, respectively) concentrations were monitored over a 90-day period in a naturally ventilated school building located at roadside in Chennai City.

Altered DNA repair, oxidative stress and antioxidant status in coronary artery disease.

Coronary artery disease (CAD) is a multifactorial disease caused by the interplay of environmental risk factors with multiple predisposing genes. The present study was undertaken to evaluate the role of DNA repair efficiency and oxidative stress and antioxidant status in CAD patients. Malonaldehyde (MDA), which is an indicator of oxidative stress, and mean break per cell (b/c) values, which is an indicator of decreased DNA repair efficiency, were found to be significantly increased in patients compared to normal controls (P less than 0.