Publications by authors named "V S Carter"
Background: Preserved ratio impaired spirometry (PRISm) represents a population with spirometry results that do not meet standardized COPD obstruction criteria, yet present with high respiratory symptom burden and might benefit from respiratory management and treatment. We aimed to determine prevalence of PRISm in US primary care patients diagnosed with COPD, describe their demographic, clinical, and CT scan characteristics.
Methods: An observational registry study utilizing the US APEX COPD registry, composed of patients diagnosed with COPD aged 35+ years.
Article Synopsis
- Oral corticosteroids (OCS) are commonly used to manage exacerbations of chronic obstructive pulmonary disease (COPD) but can lead to negative health outcomes that increase healthcare costs and resource use.
- A study analyzed data from the UK Clinical Practice Research Datalink to compare healthcare attendance and costs between COPD patients who used OCS and those who didn’t, focusing on hospital visits and costs.
- Results showed that patients who used OCS had significantly higher healthcare attendance and costs, with the increases correlating positively with the cumulative OCS dose, particularly for primary care consultations and emergency visits.
Introduction: Patients with severe asthma may be prescribed biologic therapies to improve disease control. The EVEREST study aimed to characterize the global disease burden of patients with severe asthma without access to biologics and those who have access but do not receive biologics, as well as the remaining unmet need despite use of these therapies.
Methods: This was a historical cohort study of patients with severe asthma (aged ≥18 years) in the International Severe Asthma Registry receiving Global Initiative for Asthma (GINA) 2018 step 5 treatment, or with uncontrolled disease at GINA step 4.
Background: Prior exacerbation history is used to guide initial maintenance therapy in COPD; however, the recommendations were derived from patients already diagnosed and treated.
Methods: We assessed the rates of moderate ( treated with antibiotics and/or systemic corticosteroids) and severe ( hospitalised) exacerbations in the year following diagnosis in patients newly diagnosed with COPD according to their prior history of exacerbations, blood eosinophil count (BEC) and whether maintenance therapy was started. Data were extracted from the Optimum Patient Care Research Database.