The paper presents the results of biopsy and curettage specimens from 92 patients with infertility. Histological and immunohistological (steroid receptors, Ki67, P27, and cyclin E) methods and scanning electron microscopy have been used. The substantial immunohistochemical (IHC) changes found in the endometrial implantation window in infertility are associated with the spectrum of the detected pathology.
View Article and Find Full Text PDFEndometrial scrapes and biopsy specimens from 47 females with primary and secondary infertility were studied by histological and immnohistological (estrogen and progesterone receptors, Ki67) methods. Endometrial abnormalities, such as luteal phase defect, hyperplasia, endometrial polyps, and chronic endometritis, were detected in all the patients. There were considerable changes in the expression of estrogen and progesterone receptors and impaired endometrial proliferative processes.
View Article and Find Full Text PDF9 breast fibroadenomas from females of different age who had a familial history of breast cancer were immunohistochemically studied. Having the same histological structure, the tumors differed in the expression of steroid hormone receptors, in the values of proliferation marker Ki-67 and oncomarker p53. It is concluded that the study of fibroadenoma may reveal breast carcinoma risk groups.
View Article and Find Full Text PDFA case of sygmoid endometriosis is described in a 40-year-old female. After clinical and endoscopic examination, the patient was operated for sigmoid tumor, acute obturation colon obstruction. Histologically diagnosis of intestinal wall endometriosis was established.
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