[The off-season vitamin D3 deficiency of in children and adolescents of Moscow].

The detection of season deficiency was carried out among children and adolescents residing in Moscow. It is established that vitamin D3 deficiency, in all children and adolescents comprises 89% in spring and 62% in autumn. Independently of season, the vitamin D3 deficiency is least expressed in children of early age and its most propagation takes place in adolescents.

[The evaluation of effectiveness of management of intra-laboratory flows on the basis of turnaround time].

The turnaroud time was established for biochemical and immunochemical analyses using separately standing analyzers, component parts of module system, virtually and really consolidated systems. It is discovered that the least time of results receiving is typical for analyses implemented at the module system cobas 6000. The information about turnaroud time based on records of laboratory information system, can be applied in optimizing the management of intra-laboratory flows.

[The detection of vitamin D3 deficiency in preschoolers and schoolchildren of Moscow and St. Petersburg].

The evaluation of prevalence and intensity of vitamin D3 deficiency in preschoolers and schoolchildren residing in Moscow and St. Petersburg was implemented. It is established that 63.

[Age-related changes in the level of serum bone markers in healthy children].

Age-related changes in the blood level of bone metabolic markers were compared in healthy children living in different geographical regions. The absolute value of carboxy-terminal telopeptide of type 1 collagen type 1 (beta-CrossLaps) and that of total procollagen type 1 amino-terminal propeptide (PINP) were found to depend on living conditions and the nature of changes in the serum markers of bone metabolism was related to the processes of natural growth and development in children. A child's individual growth curve can be used to identify target groups for the prevention of osteopenia.

[Plasma leptin level in patients with bronchial asthma].

The aim of this study was to measure plasma leptin level in patients with bronchial asthma (BA) and compare it with clinical features of the disease. It included 21 healthy subjects, 9 patients with extrapulmonary allergy, and 18 with partially controllable BA. Plasma leptin was measured by ELISA.