Publications by authors named "V S Albrecht"
Article Synopsis
- The 68th Benzon Foundation Symposium focused on combining mass spectrometry-based proteomics with artificial intelligence to enhance personalized medicine.
- Key discussions covered advancements in mass spectrometry technology, particularly in plasma proteomics for biomarker discovery and challenges in applying these discoveries in clinical practice.
- The potential of proteomics in areas like cancer diagnostics and neurodegenerative diseases was highlighted, along with the role of AI in managing large datasets to improve clinical decisions and outcomes.
Recent improvements in proteomics technologies have fundamentally altered our capacities to characterize human biology. There is an ever-growing interest in using these novel methods for studying the circulating proteome, as blood offers an accessible window into human health. However, every methodological innovation and analytical progress calls for reassessing our existing approaches and routines to ensure that the new data will add value to the greater biomedical research community and avoid previous errors.
View Article and Find Full Text PDFThe prerequisite for successful HLA genotyping is the integrity of the large allele reference database IPD-IMGT/HLA. Consequently, it is in the laboratories' best interest that the data quality of submitted novel sequences is high. However, due to its long and variable length, the gene HLA-DRB1 presents the biggest challenge and as of today only 16% of the HLA-DRB1 alleles in the database are characterized in full length.
View Article and Find Full Text PDFBackground: Sepsis is a life-threatening and relatively common emergency which is often recognized too late or not at all. Therefore, the "SepsisWissen" (SepsisKnowledge) project aimed to bring about changes in health care professionals' behavior in the area of sepsis prevention and early detection. It addressed the health care professionals themselves (e.
View Article and Find Full Text PDFBackground: Self-sampling of dried blood spots (DBS) offers new routes to gather valuable health-related information from the general population. Yet, the utility of using deep proteome profiling from home-sampled DBS to obtain clinically relevant insights about SARS-CoV-2 infections remains largely unexplored.
Methods: Our study involved 228 individuals from the general Swedish population who used a volumetric DBS sampling device and completed questionnaires at home during spring 2020 and summer 2021.