Publications by authors named "V Rizza"
Diabetic cardiomyopathy: pathophysiology, imaging assessment and therapeutical strategies.
Int J Cardiol Cardiovasc Risk Prev
December 2024
Diabetes mellitus (DM) is one of the most prevalent cardiovascular risk factors in the general population, being associated with high morbidity and socioeconomic burden. Diabetic cardiomyopathy (DCM) is a non-negligible complication of DM, whose pathophysiological fundaments are the altered cardiac metabolism, the hyperglycemia-triggered formation of advanced glycation end-products (AGEs) and the inflammatory milieu which are typical in diabetic patients. These metabolic abnormalities lead to cardiomyocytes apoptosis, interstitial fibrosis and mechanical cardiac dysfunction, which can be identified with non-invasive imaging techniques, like echocardiography and cardiac magnetic resonance.
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- Mitral annular disjunction (MAD) can present as either True-MAD or Pseudo-MAD, with the study identifying their prevalence in patients with mitral valve prolapse (MVP) using transthoracic echocardiography (TTE).
- Of the 603 patients studied, True-MAD was found in 7% while Pseudo-MAD was found in 37%, suggesting a significant reclassification of cases traditionally thought to be MAD.
- TTE proved to be a highly accurate and reliable tool for assessing mitral conditions, with accuracy ratings of 0.89 and strong intra/inter-rater reliability, affirming its value as a first-line assessment method in clinical settings.
Article Synopsis
- A 32-year-old woman experienced recurring migraines after having a percutaneous patent foramen ovale (PFO) closure, which was initially done due to a previous embolism.
- Transoesophageal echocardiography revealed that the original PFO closure device was partially displaced, leading to a residual interatrial shunt.
- After successfully placing a second occluder to overlap with the first, the patient reported no migraines during a 6-month follow-up, suggesting this approach effectively managed her condition.
Aims: The prevalence, the aetiologies, and the clinical features of tricuspid regurgitation (TR) in the context of concomitant degenerative mitral valve (MV) disease are poorly defined. This paper aims to assess the prevalence, determinants, and clinical consequences of TR in severe degenerative mitral regurgitation (DMR).
Methods And Results: Clinical and echocardiographic characteristics were collected among patients with severe DMR.
Background: Mitral regurgitation (MR) is frequent in patients with aortic stenosis (AS). Although primary MR is an established negative prognostic factor, whether different mechanisms of MR have different effects on outcome is currently unknown. The aim of this study was to evaluate the impact of the MR mechanism in patients undergoing transcatheter aortic valve replacement (TAVR).
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