Publications by authors named "V Rives Molina"
Lower perturbational complexity index after transcranial magnetic stimulation in schizophrenia patients.
Prog Neuropsychopharmacol Biol Psychiatry
January 2025
Background: Informational integration and differentiation of the cortex can be tested by methods such as the perturbational complexity index (PCI) combined with TMS-induced activity perturbation. The PCI is obtained by stimulating the cortex with TMS and measuring the resulting spatiotemporal cortical responses with high-density EEG.
Methods: We have compared PCI between 26 patients with schizophrenia (15 males), 15 of them First Episode (FE) (7 males), and 22 healthy controls (12 males).
Article Synopsis
- The Parque Nacional La Campana was found to have a rich microbial diversity in its soil, with a study focused on areas with sclerophyllous forests and xerophytic shrublands.
- Variation in microbial communities was influenced more by different vegetation types and soil conditions on opposing slopes rather than just the soil depth itself.
- Key microbial taxa differed significantly between the two environments, with specific fungi and bacteria thriving in each, indicating the impact of the local ecosystem on microbial life and functions.
Thermophilic microorganisms possess several adaptations to thrive in high temperature, which is reflected as biosynthesis of proteins and thermostable molecules, isolation and culture represent a great methodological challenge, therefore High throughput sequencing enables screening of the whole bacterial genome for functional potential, providing rapid and cost-effective information to guide targeted cultures for the identification and characterization of novel natural products. In this study, we isolated two thermophilic bacterial strains corresponding to LB7 and LB8, from the microbial mats in the Atacama Desert. By combining genome mining, targeted cultures and biochemical characterization, we aimed to identify their capacity to synthesize bioactive compounds with antimicrobial properties.
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- Parque Nacional La Campana (PNLC) is famous for its diverse plant and animal life, but this study focused on examining the lesser-known microbial communities present in its ecosystems.
- Researchers analyzed soil samples from different plant types found in PNLC, like sclerophyllous and xerophytic forests, using advanced DNA sequencing techniques to identify microbial composition.
- The study revealed specific microbial communities linked to various plant ecosystems, highlighting that factors like elevation and soil type significantly influence the diversity and structure of microbes in the park.
Objective: The Corollary Discharge (CD) mechanism inhibits self-generated speech sound perception, appearing disrupted in schizophrenia and potentially contributing to Anomalous Self-Experiences (ASEs). However, it remains unclear if this alteration and its correlation with ASEs extend to other psychotic disorders.
Methods: Electroencephalography was used to study the N1 Event-Related Potential (ERP) as an index of CD-mediated suppression in the auditory cortex across thirty-five participants with schizophrenia, twenty-six with bipolar disorder, and thirty healthy controls.