[Cannabis: Effects in the Central Nervous System. Therapeutic, societal and legal consequences].

The consumption of marijuana extracted from Cannabis sativa and indica plants involves an important cultural impact in Mexico. Their psychological stimulatory effect is widely recognized; their biochemical and molecular components interact with CB1 and CB2 (endocannabinoid system) receptors in various central nervous system structures (CNS) and immune cells. The psychoactive element Δ-9-tetrahydrocannabinol (THC) can be reproduced synthetically.

[Recommendations for optimising the treatment of multiple sclerosis in Latin America].

Introduction: Multiple sclerosis (MS) is the most common primary demyelinating disease affecting the central nervous system. In recent years the development of new drugs that have been shown to modify the natural history of MS have had a substantial impact on the treatment of the disease.

Aims: To harmonise and integrate the evidence available on optimising the treatment of patients with MS.

[The treatment of multiple sclerosis in Latin America: current practice and optimal standards. The findings of a survey among neurologists at an interactive workshop].

Introduction: Considerable progress has been made in the treatment of patients with relapsing-remitting multiple sclerosis (MS) over the last decade. Exactly how these changes are reflected in daily practice, however, is still not very well known.

Aim: To hold interactive workshops so as to be able to evaluate the opinions of Latin-American neurologists about the therapeutic decisions taken with regard to MS.

[Multiple sclerosis in Mexico: a multicentre study].

Introduction: Multiple sclerosis (MS) is considered to be a low prevalence disease in Mexico; its characteristics have been described in isolated studies in small populations concentrated in a single region of the country and using heterogeneous methodological tools. AIMS. In this study, our aim was define the clinical profile and some socio demographic aspects of MS in Mexico using validated homogeneous criteria and tools.

Rett's syndrome with Lennox-Gastaut pattern.

Three Latin American female patients studied in two different centers (Mexico City and Houston, Texas) had the clinical criteria of Rett's Syndrome, including progressive intellectual deterioration, stereotyped movements, loss of purposeful hand use, ataxia, and progressive disability. The three patients had normal laboratory studies including imaging studies (CT and MRI) but consistently abnormal EEGs with Lennox-Gastaut pattern. The usefulness of the EEG in the differential diagnosis and the association of this electrographic phenomenon are stressed.