Publications by authors named "V Rieu"

Article Synopsis
  • Patients with X linked agammaglobulinemia and those receiving anti-CD20 monoclonal antibodies (mAbs) for immune-mediated inflammatory diseases (IMIDs) are at increased risk for severe enterovirus (EV) infections, particularly meningoencephalitis.
  • A study collected data from nine original cases and 17 previously published cases, revealing a high occurrence of meningoencephalitis (81%) and a mortality rate of 27% among affected patients treated with multiple anti-CD20 mAbs.
  • The findings suggest that clinicians should consider EV infections in IMID patients presenting unusual symptoms and recognize that anti-CD20 mAbs can impair B-cell responses to EV infections, potentially indicating
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Primary humoral deficiency and secondary B-cell depletion may lead to prolonged Sars-Cov-2 infection due to a decreased viral clearance. Prolonged infection is mainly driven by the lack of anti-Sars-Cov-2 immunoglobulin (IVIg) especially in patients with no vaccine response. Anti-spike immunoglobulin can be provided by infusion of convalescent patients' plasma: recent studies highlighted that commercial immunoglobulin show high titers of neutralizing IgG.

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Objectives: To describe the characteristics, treatment and outcome of isolated ANCA-associated scleritis at diagnosis compared with idiopathic scleritis with negative ANCA tests.

Methods: This retrospective multicentre case-control study was performed within the French Vasculitis Study Group (FVSG) network and in three French tertiary ophthalmologic centres. Data from patients with scleritis without any systemic manifestation and with positive ANCA results were compared with those of a control group of patients with idiopathic scleritis with negative ANCA tests.

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Gorham-Stout disease (or "vanishing bone" disease) is a rare mono or polyostotic disease of unknown etiology, characterized by intraosseous angiomatous proliferation leading to bone resorption. We report the case of a 17-year-old woman presenting with symptomatic osteolytic lesions of the frontal vault. Imaging was suggestive of Gorham-Stout disease without argument for other diagnoses.

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