Publications by authors named "V Renzelli"
Neuroendocrine neoplasms of the breast: a multicenter retrospective Italian study.
Minerva Endocrinol (Torino)
December 2024
Background: The aim of our retrospective study was to describe the immunophenotypic characteristics of neuroendocrine breast neoplasm (BNEN), a peculiar and rare type of breast carcinoma.
Methods: Pathological data from 51 patients affected by BNEN were retrospectively evaluated, and 44 patients were considered eligible (7 patients with incomplete data were excluded). The patients were followed in six different Italian hospitals between 2009 and 2019.
Article Synopsis
- - A 72-year-old male with a history of advanced tongue cancer was found to have a large left adrenal mass during follow-up, which raised suspicion for metastasis.
- - After surgical removal, the mass was diagnosed as poorly differentiated hepatocellular carcinoma (HCC), despite no primary liver tumor being identified during further investigations.
- - The case highlights the importance of considering adrenal metastasis in cancer patients, as it can lead to the unexpected discovery of another underlying malignancy, such as HCC, especially in the context of liver cirrhosis.
Background: Increasing evidence suggests that diabetes increases the risk of developing different types of cancer. Hyperinsulinemia, hyperglycemia and chronic inflammation, characteristic of diabetes, could represent possible mechanisms involved in cancer development in diabetic patients. At the same time, cancer increases the risk of developing new-onset diabetes, mainly caused by the use of specific anticancer therapies.
View Article and Find Full Text PDFEndocrine-metabolic assessment checklist for cancer patients treated with immunotherapy: A proposal by the Italian Association of Medical Oncology (AIOM), Italian Association of Medical Diabetologists (AMD), Italian Society of Diabetology (SID), Italian Society of Endocrinology (SIE) and Italian Society of Pharmacology (SIF) multidisciplinary group.
Cancer Treat Rev
May 2024
Article Synopsis
- Immunotherapy using immune checkpoint inhibitors (ICI) is becoming common in cancer treatment, but managing related endocrine side effects can be challenging.
- Different scientific societies have varying guidelines concerning when to conduct endocrine testing for patients undergoing this therapy.
- A panel of experts from several Italian medical associations has developed a straightforward and practical checklist for assessing endocrine and metabolic health in cancer patients receiving immunotherapy.
Cancer management has significantly evolved in recent years, focusing on a multidisciplinary team approach to provide the best possible patient care and address the various comorbidities, toxicities, and complications that may arise during the patient's treatment journey. The co-occurrence of diabetes and cancer presents a significant challenge for health care professionals worldwide. Management of these conditions requires a holistic approach to improve patients' overall health, treatment outcomes, and quality of life, preventing diabetes complications and cancer treatment side-effects.
View Article and Find Full Text PDF