Surgery remains the primary treatment modality in the management of early-stage invasive breast cancer. Artificial intelligence (AI)-powered visualization platforms offer the compelling potential to aid surgeons in evaluating the tumor's location and morphology within the breast and accordingly optimize their surgical approach. We sought to validate an AI platform that employs dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to render three-dimensional (3D) representations of the tumor and 5 additional chest tissues, offering clear visualizations as well as functionalities for quantifying tumor morphology, tumor-to-landmark structure distances, excision volumes, and approximate surgical margins.
View Article and Find Full Text PDFCircadian rhythms, which regulate essential physiological and behavioral processes, are crucial for maintaining overall health and well-being. However, disruptions to these rhythms, particularly due to trans-meridian travel and shift work, can lead to significant health issues, including jet lag, metabolic imbalances, and neuropsychiatric disorders. In this systematic review, conducted in line with Preferred Reporting Items for Systematic Reviews and Metanalysis (PRISMA) 2020 guidelines, we explore the effectiveness of various interventions aimed at realigning circadian rhythms disrupted by such factors.
View Article and Find Full Text PDFAcute cholecystitis (AC) is a prevalent surgical emergency, particularly among elderly individuals who present with high perioperative risks. While early cholecystectomy (CCY) is the standard treatment, percutaneous cholecystostomy (PC) is proposed as an alternative for high-risk patients. This systematic review aims to evaluate the comparative safety and efficacy of CCY versus PC in managing AC among elderly and high-risk surgical patients.
View Article and Find Full Text PDFThis literature review explores the association between iron deficiency anemia and migraines, examining their prevalence, underlying pathophysiology, and therapeutic potential of iron supplementation in managing migraine symptoms. A systematic search across major academic databases, including PubMed, Google Scholar, ScienceDirect, and Science.gov, identified relevant peer-reviewed studies that focus on the link between iron deficiency anemia and migraines.
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