Publications by authors named "V R Muradova"
Article Synopsis
- Recent research highlights follicle-stimulating hormone (FSH) as a target for treating diseases like osteoporosis, obesity, and Alzheimer's, with findings showing that blocking FSH can prevent various health issues in mice.
- The development of a humanized FSH-blocking antibody called MS-Hu6 has shown promise in preventing osteoporosis in mice and has safe initial testing in monkeys, demonstrating effective localization to bone and bone marrow.
- MS-Hu6 has been optimized for stability and safety, showing no immunogenic responses in human cell cultures, making it ready for potential future human clinical trials.
Article Synopsis
- - Alzheimer's disease is more common in older women, especially during menopause, and is linked to factors like body fat, energy regulation, and bone loss.
- - In mice, reducing follicle-stimulating hormone (FSH) levels leads to decreased body fat, improved bone health, and lower cholesterol.
- - The study shows that FSH contributes to Alzheimer's symptoms by accelerating harmful protein buildup in the brain, and blocking FSH can potentially help treat Alzheimer's and related conditions.
Aim: To analyze racial disparities in Coronavirus disease (COVID-19) cases in the United States of America and discuss possible reasons behind this inequality.
Subject And Methods: We obtained estimated case counts of African-American, Caucasian, Native American, Asian and Hispanic individuals with coronavirus disease (COVID-19)infection through May 5, 2020, from publicly available data on state departments of health websites. We calculated race-specific fractions as the percentage of the total population and analyzed the reasons behind this disparity.
The objective of the present work was to analyze the current concept of the genetically predetermined condition Zivert-Kartagener's syndrome with special reference to the pathogenetic mechanisms underlying the development of this condition, its clinical picture and methods of treatment. The authors' original observations of the patients presenting with Zivert-Kartagener's syndrome are reported.
View Article and Find Full Text PDFThe authors present the currently available data on mucoviscidosis (cystic fibrosis) based on their original experience and the review of the relevant literature. Special attention is given to the pathogenetic mechanisms underlying the development of this condition, its diagnostics, and methods of treatment as exemplified by the clinical case of cystic fibrosis in an adult patient.
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