Publications by authors named "V R Gomez"

Political conflict is an essential element of democratic systems, but can also threaten their existence if it becomes too intense. This happens particularly when most political issues become aligned along the same major fault line, splitting society into two antagonistic camps. In the 20th century, major fault lines were formed by structural conflicts, like owners vs.

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Background: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a genetic arrhythmic syndrome caused by mutations in the calcium (Ca) release channel ryanodine receptor (RyR2) and its accessory proteins. These mutations make the channel leaky, resulting in Ca-dependent arrhythmias. Besides arrhythmias, CPVT hearts typically lack structural cardiac remodeling, a characteristic often observed in other cardiac conditions (heart failure, prediabetes) also marked by RyR2 leak.

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Background: Dissecting intracranial aneurysms (DIAs) have been treated through endovascular reconstructive manners, such as flow diverters (FDs) and stent-assisted coiling (SAC). Notably, no robust evidence has compared both approaches. Hence, the authors conducted a meta-analysis to compare their outcomes.

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Article Synopsis
  • - The study investigates the process of using in-house CAD/CAM technology for head and neck cancer surgeries, particularly focusing on 3D printing biomodels and cutting guides.
  • - The goal is to create a validated, cost-effective workflow for a 3D Printing Department in a Spanish university hospital using free software, comparing it with outsourcing options.
  • - Results show that an in-house 3D Printing Department is practical, offering benefits like cost savings and faster production times, ultimately improving surgical procedures in the healthcare system.
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Peroxisomal biogenesis disorders (PBD) are autosomal recessive disorders caused by loss-of-function mutations of one of the genes responsible for peroxisomal formation. Impaired peroxisome assembly causes severe multisystemic failure with patient phenotypes ranging from epilepsy, liver disease, feeding issues, biochemical abnormalities, and neurodegeneration. Variants in the same gene can produce wide differences in severity, ranging from individuals with death in the first year of life to adults with milder complications.

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