Evaluation of a passive back-support exoskeleton in bed-to-chair patient handling tasks.

This study assessed the impact of a passive back-support exoskeleton (Laevo V2.5; Laevo, Netherlands) on trunk and hip postures, lower back muscle activity and heart rate during four common patient handling tasks: task 1, lying to sitting; task 2, sitting to standing; task 3, standing to sitting; task 4, bed-to-wheelchair transfer. Eight participants performed these tasks with and without the exoskeleton.

Protective effects of and extract on oxaliplatin-induced neuropathy via modulation of NF-κB signaling.

Oxaliplatin is a third-generation anticancer agent with better efficacy, lower toxicity, and a broad spectrum of antineoplastic activity. Its use is frequently associated with chronic oxaliplatin-induced neuropathy (OIN), a cumulative phenomenon manifesting as loss of sensation, paresthesia, dysesthesia, and irresolvable fluctuations in proprioception that greatly affect the patients' quality of life. The inevitable nature and high incidence of OIN, along with the absence of efficacious preventive agents, necessitate the development of effective and reliable protective options for limiting OIN while maintaining anticancer activity.

Characterising ATP binding activity of PilB ATPase of MR-1 using a molecular modeling and simulations approach.

This study characterises the interaction between the type IV pilus assembly PilB ATPase of a versatile electroactive microbe, MR-1, and ATP using tools. PilB ATPase, which is associated with different cellular activities, is a protein subunit of type IV pili. A composite model of the protein was generated using the I-TASSER Web server and its stereochemical quality was evaluated using PROCHECK.

The naturalistic paradigm: An approach to studying individual variability in neural underpinnings of music perception.

Music listening is a dynamic process that entails complex interactions between sensory, cognitive, and emotional processes. The naturalistic paradigm provides a means to investigate these processes in an ecologically valid manner by allowing experimental settings that mimic real-life musical experiences. In this paper, we highlight the importance of the naturalistic paradigm in studying dynamic music processing and discuss how it allows for investigating both the segregation and integration of brain processes using model-based and model-free methods.