Rapid On-Site Digital Histopatholocal Evaluation (RODE) on Endobronchial Ultrasound (EBUS) Mediastinal Lymph Node Cryobiopsy Sampling Using Confocal Laser Microscopy-A Proof-Of-Concept Study.

The current standard for determining sample adequacy during Endobronchial Ultrasound guided Mediastinal Sampling is ROSE (Rapid on-site Evaluation) on samples obtained by Fine needle Aspiration. There is an increasing interest in Mediastinal Lymph node cryobiopsy, where tissue samples are obtained using a 1.1 mm cryoprobe.

The clinical meaning of the UIP pattern in fibrotic hypersensitivity pneumonitis on cryobiopsy: A multicentre retrospective study.

Fibrotic hypersensitivity pneumonitis (f-HP) is an interstitial lung disease in which various antigens in susceptible individuals may play a pathogenetic role. This study evaluates the role of transbronchial lung cryobiopsy (TBLC) and bronchoalveolar lavage (BAL) in identifying a UIP-like pattern and its association with fibrosis progression. We conducted a multicentre retrospective cohort study of patients diagnosed with f-HP who underwent BAL and TBLC between 2011 and 2023.