Publications by authors named "V Perez-Munuzuri"

Background: High-field magnetic resonance imaging (MRI) is a powerful diagnostic tool but can induce unintended physiological effects, such as nystagmus and dizziness, potentially compromising the comfort and safety of individuals undergoing imaging. These effects likely result from the Lorentz force, which arises from the interaction between the MRI's static magnetic field and electrical currents in the inner ear. Yet, the Lorentz force hypothesis fails to explain observed eye movement patterns in healthy adults fully.

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Marine plastic litter is an emerging global problem with serious environmental and economic consequences. Once deposited in the ocean, it is transported by currents for long periods of time, making it a transboundary problem. The variety of plastic items makes the study of their transport in the ocean system a challenge.

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Background And Objective: Fractional Flow Reserve (FFR) is generally considered the gold standard in hemodynamics to assess the impact of a stenosis on the blood flow. The standard procedure to measure involves the displacement of a pressure guide along the circulatory system until it is placed next to the lesion to be analyzed. The main objective of the present study is to analyze the influence of the pressure guide on the invasive FFR measurements and its implications in clinical practice.

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Article Synopsis
  • The study investigates why some patients with benign paroxysmal positional vertigo (BPPV) do not respond to the standard Epley maneuver, suggesting that individual anatomical differences in the membranous labyrinth may play a significant role.
  • Using advanced 3D imaging and mathematical modeling, researchers simulated the Epley maneuver to analyze the movement of otoconia (tiny particles) and fluid within the labyrinth.
  • The findings showed that otoconia often fail to reach the desired location, indicating that longer resting times and alternative rotation angles may enhance treatment effectiveness by preventing complications.
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The Head Impulse Test, the most widely accept test to assess the vestibular function, comprises rotations of the head based on idealized orientations of the semicircular canals, instead of their individual arrangement specific for each patient. In this study, we show how computational modelling can help personalize the diagnosis of vestibular diseases. Based on a micro-computed tomography reconstruction of the human membranous labyrinth and their simulation using Computational Fluid Dynamics and Fluid-Solid Interaction techniques, we evaluated the stimulus experienced by the six cristae ampullaris under different rotational conditions mimicking the Head Impulse Test.

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