Gabapentin and alprazolam pretreatment enhance sedation and reduce propofol requirements but do not improve intravenous catheter placement in cats undergoing elective ovariohysterectomy.

Objective: This study aimed to evaluate whether pretreatment with gabapentin or alprazolam in cats increases sedation, facilitates intravenous catheter placement (IVCP), or reduces propofol requirements for intubation compared to placebo.

Methods: All cats that participated in this prospective, randomized, blinded, controlled clinical trial were admitted for elective ovariohysterectomy at a veterinary teaching hospital from 2022 to 2023. The cats were healthy, were ≥ 6 months old, and weighed > 3 kg.

A new method for the estimation of stochastic epidemic descriptors reinforced by Kalman-based dynamic parameter estimation. Application to mpox data.

In the realm of epidemiology, it is essential to accurately assess epidemic phenomena through the adoption of innovative techniques that yield reliable predictions. This article introduces an advanced method that merges the Extended Kalman Filter approach with recursive algorithms to compute critical stochastic attributes important for evaluating epidemics. A new three-dimensional discrete Markov process is presented, according to which the total number of infections, deaths, and the duration of epidemic outbreaks are estimated.

Use of Gabapentin or Alprazolam in Cats during Postoperative, Short-Term Hospitalization.

This prospective, randomized study aimed to assess the anxiolytic efficacy of gabapentin or alprazolam in cats during short-term postoperative hospitalization. Sixty cats were randomly assigned to three groups (gabapentin-treated [100 mg per cat], alprazolam-treated [0.125 mg per cat], or placebo-treated), with treatments administered twice daily for two days.

Recent advancements and applications of deep learning in heart failure: Α systematic review.

Background: Heart failure (HF), a global health challenge, requires innovative diagnostic and management approaches. The rapid evolution of deep learning (DL) in healthcare necessitates a comprehensive review to evaluate these developments and their potential to enhance HF evaluation, aligning clinical practices with technological advancements.

Objective: This review aims to systematically explore the contributions of DL technologies in the assessment of HF, focusing on their potential to improve diagnostic accuracy, personalize treatment strategies, and address the impact of comorbidities.

Isoflurane treatment for refractory and super-refractory status epilepticus in dogs.

Introduction: Resistant epileptic episodes, such as refractory status epilepticus (RSE) and super-refractory status epilepticus (SRSE), are neurological emergencies that require immediate medical treatment. Although inhalational anesthetics, such as isoflurane (ISO), have been proposed as a means of seizure control in dogs, there is currently a lack of both experimental and clinical studies on this subject.

Study Design: This is a retrospective clinical study.