Publications by authors named "V Panzarella"
Background/objectives: The diagnosis of oral potentially malignant disorders (OPMDs) and oral squamous cell carcinoma (OSCC) represent a significant challenge in oral medicine. Optical coherence tomography (OCT) shows promise for evaluating oral tissue microstructure but lacks standardized diagnostic protocols tailored to the structural variability and lesions of oral mucosa.
Methods: This cross-sectional observational study aims to evaluate the diagnostic accuracy of targeted biopsy-based and site-coded OCT protocols for common OPMDs and OSCC.
Article Synopsis
- HPV is a major cause of oropharyngeal cancer, and detecting it in oral squamous cell carcinoma (OSCC) is important for diagnosis and treatment.
- This study evaluated two non-invasive methods, oral rinse and oral sponge, for detecting HPV DNA in 26 patients with confirmed OSCC.
- Results showed that the oral sponge method was more effective, with higher specificity (100%), sensitivity (85.7%), and accuracy (96.2%) compared to oral rinse, suggesting it could improve HPV detection in clinical settings.
Article Synopsis
- The study looked at issues in the mouth and throat caused by drugs and vaccines in Italy from 2019 to 2021.
- Out of over 67,000 cases, about 2,773 had throat problems, mostly in adult females, and most were not serious.
- The findings showed that many problems related to drugs were reported more often than those from vaccines, and there is a need for better reporting and training for health care workers.
Background: The prevalence of oral human papillomavirus (HPV) in the healthy population and patients with oral diseases such as oral squamous cell carcinoma (OSCC), oral potentially malignant disorders (OPMDs), and oral benign lesions (BL), is not consistently described in the literature, with scarce and often heterogeneous data. In addition, the efficacy of HPV prophylactic vaccines in preventing HPV-related oral disorders has been scarcely investigated.
Methods: The prevalence of HPV and the potential impact of vaccines were analyzed in 1,415 oral rinse specimens, collected over 10 years and grouped into four categories based on histological/clinical diagnosis.
Objective: This paper aims to describe the 2023 update position paper on MRONJ developed by the Italian Societies of Oral Pathology and Medicine (SIPMO) and of Maxillofacial Surgery (SICMF).
Methods: This is the second update following the 2013 and 2020 Italian position papers by the Expert panel, which is a representation of the two scientific societies (SIPMO and SICMF). The paper is based on an extensive analysis of the available literature from January 2003 to February 2020, and the subsequent review of literature conducted between March 2020 and December 2022 to include all new relevant published papers to confirm or modify the previous set of recommendations.