Publications by authors named "V POPESCU"

Melia azedarach L. is a Meliaceae that has shown important insecticidal activities. However, few researchers have extensively studied the toxicology of aqueous extracts of M.

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This work focuses on L. aerial parts (AP) and roots (R) extracts, investigating the anti-inflammatory and antioxidant potential of the two organs in comparison. At dosages between 1.

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Article Synopsis
  • * Machine learning models were applied to predict confirmed disability progression after two years, achieving a ROC-AUC score of 0.71, indicating moderate accuracy, while historical disability was found to be a stronger predictor than treatment or relapse history.
  • * The research followed strict guidelines and made its coding accessible for others to facilitate future benchmarking in predicting disability progression in MS patients.
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Article Synopsis
  • Many patients with multiple sclerosis (MS) still show gradual deterioration of symptoms even when on treatment that prevents relapses, indicating the need for more comprehensive understanding beyond traditional views of MS progression.
  • The authors introduce a new term, smouldering-associated-worsening (SAW), which refers to ongoing physical and cognitive decline caused by underlying pathological processes that haven’t been adequately addressed in therapy.
  • They also suggest ways to monitor SAW using clinical, radiological, and biological markers, while emphasizing the importance of integrating findings on smouldering MS into both clinical practice and future research.
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