[OPISTHORCHIASIS AS A PROMOTER OF GASTRIC CARCINOGENESIS].

The paper presents an experimental model of gastric cancer in the presence of chronic opisthorchiasis, which has been created to study its possible role in gastric carcinogenesis. The performed investigation has supported the hypothesis that opisthorchiasis plays a promoting role in the development of experimental gastric cancer. A larger number of experimental hamsters receiving the carcinogen methylnitronitrosoguanidine (MNNG) developed earlier gastric tumors in.

Is skilled technique characterized by high or low variability? An analysis of high bar giant circles.

There is conflicting evidence as to whether skilled performance is associated with lower or higher movement variability. The effect of skill level and task difficulty on movement variability during gymnastics swinging was investigated. Four male gymnasts ranging in skill from university standard through to international medallist performed 10 consecutive regular giant circles and 10 double straight somersault dismounts preceded by accelerated giant circles while kinematic data were recorded.

LDL-apheresis on affine haemosorbents.

There were synthesized new hemosorbents for selective removal of LDL, based on macroporous silica, immobilised by heparine (sorbent 1) and chytozane-sulphate (sorbent 2). Experimental data showed satisfactory hemo- and biocompatibility of the new sorbents. No significant alterations in biochemical parameters were observed.

Reactivity of the sulfhydryl groups of soluble succinate dehydrogenase.

Soluble succinate dehydrogenase prepared by butanol extraction reacts with N-ethylmaleimide according to first-order kinetics with respect to both remaining active enzyme and the inhibitor concentration. Binding of the sulfhydryl groups of the enzyme prevents its alkylation by N-ethylmaleimide and inhibition by oxaloacetate. A kinetic analysis of the inactivation of alkylating reagent in the presence of succinate or malonate suggests that N-ethylmaleimide acts as a site-directed inhibitor.