A 10 W level master oscillator power amplifier (MOPA) laser with pulse repetition rate up to 1 MHz and 75-95 ps pulse duration was developed based on a passively -switched : microchip 1064 nm laser as a master oscillator. A double-rod double-end-pumping configuration of two-pass Nd:YAG ring power amplifier was used to achieve high gain, near-Fourier-transform-limited pulses, and laser beam quality factor =1.27 along both the horizontal and vertical directions.
View Article and Find Full Text PDFThe HIV cascade model can be used as an epidemiological surveillance tool and for assessing the quality of medical care for HIV-positive people. It is possible to use the model for the entire population of people living with HIV, in various socio-demographic groups, by region, years and other indicators. This article describes the features of a HIV cascade model depending on the goals for its use.
View Article and Find Full Text PDFBackground: HIV infection is a major health problem in Russia. We aimed to assess HIV prevalence in different population groups and to compare the characteristics of 4th generation immunoassays from Abbott, Bio-Rad, Vector-Best, Diagnostic Systems, and Medical Biological Unit.
Methods: The study included 4452 individuals from the general population (GP), 391 subjects at high risk of HIV infection (HR) and 699 with potentially interfering conditions.
Using genetic engineering methods the expression vectors structures have been designed to produce recombinant proteins TnaCheY and Tna CheY-mut, the homologues of the chemotaxis protein CheY from the hyperthermophilic organism Thermotoga naphthophila in Escherichia coli BL21(DE3) cells. The cultivation conditions of transformed strains were optimized. The influence of episomal expression of the heterologous chemotaxis protein CheY on growth kinetics parameters of the culture of mesophilic bacteria E.
View Article and Find Full Text PDFAn end-pumped Nd:YAG 946 nm laser with pulse duration of 1.6 ns, output energy of 2.5 mJ, and pulse repetition rate of 50 Hz is described.
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