miR-210: A non-invasive biomarker for hypoxia-driven lung cancer diagnosis and therapy.

Lung cancer is one of the major cancer-related deaths in the world due to the low success rate in invasive diagnostic procedures and late staging. Hypoxia-associated molecular signatures have received attention due to a growing demand for non-invasive prognostic biomarkers, and miR-210 has been repoured as the only viable candidate. Tumor hypoxia is a characteristic of highly malignant lung cancer, and hypoxia-inducible factors increase miR-210 in this process as a way of allowing cancer cells to inhabit low oxygen conditions and grow further in lung cancer.

Plant-derived terpenoids modulating cancer cell metabolism and cross-linked signaling pathways: an updated reviews.

Cancer is a critical health issue that remains a predominant cause of mortality globally. It is a complex disease that may effectively regulate many signaling pathways and modify the metabolism of the body to evade the immune system. Understanding neoplastic metabolic reprogramming as a hallmark of cancer has facilitated the creation of innovative metabolism-targeted treatment strategies.

The Microbiota-Gut-Brain Axis in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Narrative Review of an Emerging Field.

The intricate relationship between gut microbiota and the brain has emerged as a pivotal area of research, particularly in understanding myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). This complex condition is characterized by debilitating fatigue, cognitive dysfunction, and a wide array of systemic manifestations, posing significant challenges for diagnosis and treatment. Recent studies highlight the microbiota-gut-brain axis as a crucial pathway in ME/CFS pathophysiology, suggesting that alterations in gut microbial composition may impact immune responses, neurochemical signaling, and neuronal health.

Tuning the thermodynamic and kinetic performance of Fenton process - effects of dissolved anions/gases and temperature.

Inorganic anions such as chloride (Cl), nitrate (), sulfate (), carbonate (), bicarbonate (), dihydrogen phosphate (), fluoride (F) are ubiquitous in water matrices, play a significant role in the degradation of organic pollutants by Fenton process. In the present study, the performance of Fenton process in the presence of these anions was studied using phenol as a model compound along with the underlying mechanism and their tolerance limit. The presence of these anions affects the rate constant of the Fenton process and decreases in the following order, ---Cl >  >  >  > F.

3T dilated inception network for enhanced autism spectrum disorder diagnosis using resting-state fMRI data.

Autism spectrum disorder (ASD) is one of the complicated neurodevelopmental disorders that impacts the daily functioning and social interactions of individuals. It includes diverse symptoms and severity levels, making it challenging to diagnose and treat efficiently. Various deep learning (DL) based methods have been developed for diagnosing ASD, which rely heavily on behavioral assessment.