HMG-B transcription factors of unicellular opisthokonts and their relatedness to the Sox-Tcf/Lef-Mata proteins of Metazoa and fungi.

A phylogenetic analysis of transcription factors of the Sox-Tcf/Lef-Mata (STM) family of the HMG-B superfamily was carried out in order to clarify the evolutionary roots of the Wnt signaling pathway in unicellular organisms. The data set for analysis included protein sequences of metazoans, fungi, unicellular opisthokonts, apusomonads and amoebozoans. The topology of the phylogenetic tree suggests that STM-related proteins arose in the common ancestor of Opisthokonta and Amoebozoa, two of amoebozoan STM proteins are sister-related to opisthokont ones and the three known lineages of STM transcription factors (STM family in narrow sence) are found in Opisthokonta only.

[Professor Joachim Albarran. Urologist and scientist ahead of his time].

The article analyzes the scientific and practical activities of the prominent French urologist Professor Joachim Albarran (1860-1912). It is noted that a student of the founder of French urology F. Guyon I.

Role of anaerobic bacteria in simian enteric diseases.

Screening of monkeys for anaerobic bacteria showed that the incidence of non-spore-forming anaerobes was 2.0-2.5 times higher than that of clostridia.

Etiologic structure of bacterial intestinal infections in monkeys of Adler breeding center.

We studied etiologic structure of bacterial intestinal infections in monkeys of Adler nursery. A total of 533 monkeys with diarrhea syndrome and monkeys dead from intestinal infections, as well as clinically healthy monkeys and animals dead from other pathologies were examined by bacteriological and molecular-genetic methods. Pathogenic enterobacteria Shigella and Salmonella and microaerophile Campylobacter were found in 5 and 19%, respectively.

[Phylogenetic analysis of the mycoplasma isolated from the Javanese macaque (M. fascicularis)].

The nucleotide sequence of the fragment of 16S-aRNA of mycoplasma was determined. The fragment was identified using the PCR method in the urogenital scrape of the Javanese macaque (M. fascicularis).