[The characteristics of the pharmacotherapy for patients with ischemic heart disease and hypertension in relation to age].

On the basis of literary and own findings the authors discuss disputable problems of the pharmacotherapy of ischemic heart disease and hypertensive disease in the age aspect including patients over 60 years of age. Approaches are analyzed to individual choice of adequate pharmacotherapy, criteria of selection and dosages with special emphasis of adreno-beta-blockaders and calcium antagonists as well as criteria of evaluation of pharmacotherapy.

[Beta-adrenoblockaders and calcium antagonists in the treatment of patients with ischemic heart disease combined with hypertension].

The authors studied 67 patients with ischemic heart disease associated with hypertensive disease and revealed that the use of beta-adrenoblockaders and calcium antagonists resulted in a reduction of the manifestations of the disease, increase of physical load tolerance, optimization of its hemodynamic and oxygen provision. In patients under 60 years of age of beta-adrenoblockaders resulted in an increase of the myocardial contractility. This was not observed in those over 60 years of age.

[Mathematical analysis of the interrelations of the indicators of lipid metabolism and parameters of the oxygen transport system in patients with ischemic heart disease].

Mathematical processing of research results (correlation, multifactorial and cluster analyses) has demonstrated intricate relationships between blood lipid composition and parameters of hemodynamic and oxygen support of exercise, undetectable by routine statistical procedures, in coronary patients. Coronary patients with hyperlipoproteinemia (HLP) showed inadequately strained and uneconomical cardio-respiratory operation in the course of exercise. The pattern of hemodynamic and oxygen support of exercise was similar in HLP patients with cardialgia and coronary HLP patients whose coronary reserve was mildly limited.