Publications by authors named "V O Pakhomova"

Article Synopsis
  • Low-quality transplants affected by hypoxic injury can result in complications after surgery.
  • This research uses mathematical modeling to analyze how oxygen absorption through the liver impacts its metabolism when oxygen levels are low.
  • Findings indicate that lower oxygenation of the perfusion medium reduces oxygen uptake, requiring more energy for the liver's metabolism, while energy resources are optimally allocated among various metabolic processes.
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Biochemistry of bioluminescence of the marine parchment tubeworm has been in research focus for over a century; however, the results obtained by various groups contradict each other. Here, we report the isolation and structural elucidation of three compounds from algae, which demonstrate bioluminescence activity with luciferase in the presence of Fe ions. These compounds are derivatives of polyunsaturated fatty acid peroxides.

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We studied the distribution of ferrihydrite nanoparticles isolated from bacteria Klebsiella oxytoca in the whole body in vivo and in a cultured isolated organ (liver). The possibility of controlling these nanoparticles in the body using a magnetic field was assessed. One hour after intravenous injection of ferrihydrite nanoparticles to mice, their accumulation was observed in the liver, lungs, and kidneys.

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This paper presents the preliminary results of the separation of the Chaetopterus variopedatus bioluminescent system into luciferin and luciferase and a brief description of some of their properties.

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The objective was to study blood Zinc levels and hair Zinc content in three subsets of 40 naive patients (29 boys) with childhood onset GH deficiency (isolated total GHD, partial GHD, syndrome biological inactive GH). Our data showed that GHD in children and adolescents, independently of GHD severity and etiology, is associated with significant decrease of blood zinc level (P < 0.05).

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