[Characteristics of patients with drug-resistant epilepsy in a tertiary hospital].

Introduction: Drug-resistant epilepsy has a cumulative incidence between 14 and 20% of patients with epilepsy. It is associated with more comorbidities and with higher healthcare expenditure and impact on quality of life.

Patients And Methods: A retrospective longitudinal descriptive study was performed covering the period from 01/01/2010 to 02/28/2024.

Hydrocephalus in pyridoxine-dependent epilepsy: New case and literature review.

Introduction: Pyridoxine-dependent epilepsy (PDE) is a rare disorder of the lysine metabolism, characterized by a pharmacoresistant epileptic encephalopathy that usually begins in the neonatal period. However, its phenotypic spectrum is wide and not limited to seizures. We report a new case of PDE who developed hydrocephalus, along with an exhaustive review of the literature.