Publications by authors named "V Nardicchi"
Article Synopsis
- Study investigates the relationship between urinary levels of S100B and Tau proteins in infants and future neurodevelopmental outcomes, particularly in those born preterm or with intrauterine growth restriction (IUGR).
- Results show that higher levels of S100B and lower levels of Tau in these infants correlate with poorer cognitive and motor skills by age two, though their relation to brain volume is weak.
- The findings suggest that monitoring urinary levels of S100B and Tau, alongside brain growth indicators, could help identify infants at risk for delayed neurodevelopment.
In Vietnam, two types of traditional medicine (TM) are practiced: thuoc nam, medicine of the South, and thuoc bac, medicine of the North, both of which are largely based on herbal drugs used by different Vietnamese ethnic groups. This review presents recently published information from various databases regarding TM, especially herbal drugs, and its integration with Western medical practices outside and inside Vietnam. We first discuss the integration of traditional and modem health concepts by Vietnamese immigrants living outside Vietnam.
View Article and Find Full Text PDFWe proposed that group IIA secretory phospholipase A(2) (GIIA) participates in neuritogenesis based on our observations that the enzyme migrates to growth cones and neurite tips when PC12 cells are induced to differentiate by nerve growth factor (NGF) (Ferrini et al., Neurochem Res 35:2168-2174, 2010). The involvement of other secretory PLA(2) isoforms in neuronal development has been suggested by others but through different mechanisms.
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- OnabotulinumtoxinA (onab/A) injections into the detrusor muscle have been shown to improve symptoms of detrusor overactivity (DO) by significantly increasing maximum cystometric capacity, regardless of whether DO is neurogenic or idiopathic.
- Recent research indicates that nerve growth factor (NGF) may be involved in the urgency and DO response, with the study finding that onab/A treatment reduces NGF protein levels while increasing the gene expression of NGF and its receptors (TRPV1, TrkA, and p75).
- While no clear correlation was established between the decrease in NGF and the improvements in bladder capacity, these findings suggest that onab/A might influence NGF dynamics, pointing to the
Aim Of The Study: Botulinum toxin A (BoNT/A) has been recently used in the treatment of benign prostatic hyperplasia due to its apoptotic activity on prostatic epithelium but few data exist on this issue in prostate cancer. Also no information exist on the eventual modulation exerted by the neurotoxin on Phospholipase A2 (PLA2) expression in prostate cancer. The aim of this study was to evaluate the activity of BoNT/A on cell growth and expression of PLA2 in prostate cancer lines.
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