Protective effects of postconditioning in transvaginally created pneumoperitoneum.

There are reports of ischemic complications in clinical practice after laparoscopy using pneumoperitoneum. Conditioning has a beneficial effect for various ischemic diseases. This experimental study was designed to evaluate the effects of postconditioning in transvaginally created pneumoperitoneum.

Promotion of tumor cell migration by extracellular matrix proteins in human pancreatic cancer.

Objectives: The pathogenesis of pancreatic carcinoma is driven by the tumor cells ability to migrate causing invasion and metastases. The correlation between the aberrant expression of basement membrane proteins and the process of tumor invasion and metastasis has not been fully determined.

Methods: In the present study, the influence of laminin, fibronectin, and collagen type IV on migratory activity of 5 different cell lines has been investigated at the level of a single tumor cell using 3-dimensional time-lapse microscopy.

Expression of YPEL1 in pancreatic cancer cell lines and tissues.

YPEL1 is a nuclear protein that is suggested to be involved in mesenchymal to epithelial-like transition during tissue development. Recently we have identified YPEL1 as a gene whose expression is deregulation in perineural invasive pancreatic cancer cells. In this study we assessed the expression of YPEL1 in normal and diseased pancreatic tissues and pancreatic cancer cell lines.

[Comparative evaluate of methods of placement of polypropylene meshes in alloplastic of incisional hernias].

Treatment results in 107 patients with incisional hernias were analyzed. All patients undergoing abdominal wall grafting with use of cellular polypropylene implant. Patients were divided into 2 groups.