Morphological characteristics of tissue reaction in the zone of "Cousin" unwoven polypropylene endoprosthesis implantation.

Comparative histological and electron microscopic study of mouse tissues at the site of implantation of Cousin mesh and unwoven polypropylene endoprostheses was carried out. Implantation of unwoven endoprosthesis was associated with more pronounced inflammatory reaction with longer elimination of neutrophilic granulocytes and macrophages from the adjacent tissues. The growth of connective tissue components between the implant fibers with the formation of fine connective tissue capsule enveloping the prosthesis was observed during earlier periods of the experiment.

Tissue reaction to implantation of light polypropylene meshes.

Comparative histological and electron-microscopic studies of tissues at the site of implantation of Vypro and Ultrapro polypropylene mesh endoprostheses and the meshes coated by fibroblasts were carried out. Tissue reaction to implantation of meshes coated by fibroblasts was more pronounced, particularly during the early period, and the process of connective-tissue capsule formation and implant growth was more rapid. The meshes integrated with the adjacent tissues at the site of implantation, which recommends them for clinical use.